Check-in is from 1400 hours. Check-out is to be completed by 1030 hours.


We accept all major credit cards (no surcharges).


We operate a no-smoking policy throughout the establishment.


Centrally-located and well-appointed, the Isis Guest House provides you with the perfect accommodation during your stay in the world-famous City of Dreaming Spires, Oxford.


Free access to super-fast broadband is available.


Served from 7.45am – 9.30am daily. Orange Juice, Grapefruit Segments, Choice of cereals, Cotswold Sausage, Bacon, Mushrooms, Hash Brown, Tomato, Egg - fried, poached or scrambled, Toast and Preserves, Tea or Coffee.


Our friendly reception staff and porters are on hand 24 hours a day to welcome you and make your stay with us comfortable and enjoyable.

Call us now on 01865 613 700 or E-Mail us at

The Isis Guest House, Oxford looks forward to welcoming you.

"Less than 10 minutes walk to central Oxford"

Centrally-located and well-appointed, the Isis Guest House provides you with the perfect accommodation during your stay in the world-famous City of Dreaming Spires, Oxford. Less than 10 minutes walk to central Oxford, you will also enjoy easy access by road to historic Blenheim Palace, Stratford upon Avon, Bladon, Woodstock, the beautiful Cotswolds, Cheltenham, The Chilterns, Bicester Village Outlet Centre (15 mins by train), Heathrow Airport and London. We are open to guests during July, August and September. Our 37 rooms provide single, twin, double and family rooms with standard and en-suite facilities to suit most people's needs. Group bookings are most welcome. Unpack your bags because The Isis is an ideal base while you explore the wealth of local attractions on your doorstep. Choose to tour by foot, cycle, bus, train, car or even a relaxing punt down the river. With access to fast and regular public transport links just around the corner, we are an ideal base for day trips to London.

Find Us

  • +44 (0)1865 613700
  • Isis Guest House, 45-53 Iffley Road, Oxford, OX4 1ED

A selection of some of our recent reviews on Trip Advisor

I stayed at ISIS for four nights and overall, it was even better than I expected - the room was clean, the breakfast - traditional English breakfast - well served and tasty. WiFi access is free and available in all rooms. Location is convenient, rather close to the center, quiet place, bus stop just nearby. Highly recommended.

Toma B

Stepantsminda, Georgia
We arrived in Oxford and went to the tourism office to get assistance in finding a hotel. The Isis had rooms available for £45 per night. As others have mentioned, the Isis is student housing for St. Edmund Hall during the school year, so is only available to the general public when school isn't in session...I believe July-September. The rooms were spotless, there was a nice bag of toiletries in the room, and the breakfast was good. Our rooms were in the front, but it was very quiet. The WC and showers were down the hall on this visit. When we returned later in the week, the main guesthouse was full, but they had rooms (en-suite, but without breakfast ) in another building a block away. The location is perfect, with restaurants, pubs, botanical garden, shopping and major sites nearby and we could walk everywhere in Oxford that we wished to go. The five-star rating is based on the value and location for what can be a pricey city to stay in!


Minnetonka, Minnesota
Oxford is not cheap! and although I would not normally pay so much for a B&B, I am pleased I chose this one. Part of St Edmunds College during most of the year, it has everything you need. Clean, good beds, adequate on-suite. The breakfast is very good and well cooked. The room had plenty of tea and coffee (a pet hate of mine is lack of tea and coffee in hotels) and a gift of toiletries bearing the 'St Edmunds' logo. It was also ideal as my Granddaughter is looking to get into Oxford next year and this gave her an idea of year 2 accommodation. There is a bus stop over the road, or a short walk into Oxford centre. We also went on the tourist open top bus which runs from Sainsburys (close by). We were also able to leave our luggage after check out which made sightseeing a lot easier.


Coventry, United Kingdom

We are open to guests during July, August and September, however bookings can be made all-year round for these Summer months.

If you have booked through University Rooms, please see here for their full terms and conditions.